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CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy

BACKGROUND: The pro-tumorigenic effects of the insulin-like growth factor receptor (IGF1R) are well described. IGF1R promotes cancer cell survival and proliferation and prevents apoptosis, and, additionally it was shown that IGF1R levels are significantly elevated in most common human malignancies i...

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Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Rostoker, Ran, Ben-Shmuel, Sarit, Rashed, Rola, Shen Orr, Zila, LeRoith, Derek
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867988/
https://ncbi.nlm.nih.gov/pubmed/27179633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0711-7
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