CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy

BACKGROUND: The pro-tumorigenic effects of the insulin-like growth factor receptor (IGF1R) are well described. IGF1R promotes cancer cell survival and proliferation and prevents apoptosis, and, additionally it was shown that IGF1R levels are significantly elevated in most common human malignancies i...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Breast Cancer Res
Hlavní autoři: Rostoker, Ran, Ben-Shmuel, Sarit, Rashed, Rola, Shen Orr, Zila, LeRoith, Derek
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867988/
https://ncbi.nlm.nih.gov/pubmed/27179633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0711-7
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