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CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy

BACKGROUND: The pro-tumorigenic effects of the insulin-like growth factor receptor (IGF1R) are well described. IGF1R promotes cancer cell survival and proliferation and prevents apoptosis, and, additionally it was shown that IGF1R levels are significantly elevated in most common human malignancies i...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer Res
Autori principali: Rostoker, Ran, Ben-Shmuel, Sarit, Rashed, Rola, Shen Orr, Zila, LeRoith, Derek
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867988/
https://ncbi.nlm.nih.gov/pubmed/27179633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0711-7
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