CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy

BACKGROUND: The pro-tumorigenic effects of the insulin-like growth factor receptor (IGF1R) are well described. IGF1R promotes cancer cell survival and proliferation and prevents apoptosis, and, additionally it was shown that IGF1R levels are significantly elevated in most common human malignancies i...

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Bibliographic Details
Published in:Breast Cancer Res
Main Authors: Rostoker, Ran, Ben-Shmuel, Sarit, Rashed, Rola, Shen Orr, Zila, LeRoith, Derek
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867988/
https://ncbi.nlm.nih.gov/pubmed/27179633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0711-7
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