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BET and BRAF inhibitors act synergistically against BRAF‐mutant melanoma
Despite major advances in the treatment of metastatic melanoma, treatment failure is still inevitable in most cases. Manipulation of key epigenetic regulators, including inhibition of Bromodomain and extra‐terminal domain (BET) family members impairs cell proliferation in vitro and tumor growth in v...
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| Publicado en: | Cancer Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867668/ https://ncbi.nlm.nih.gov/pubmed/27169980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.667 |
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