Detection of Mutant BRAF Alleles in the Plasma of Patients with Metastatic Melanoma

Mutations in the BRAF oncogene at amino acid 600 have been reported in 40 to 70% of human metastatic melanoma tissues, and the critical role of BRAF in the biology of melanoma has been established. Sampling the blood compartment to detect the mutational status of a solid tumor represents a highly in...

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Autors principals: Yancovitz, Molly, Yoon, Joanne, Mikhail, Maryann, Gai, Weiming, Shapiro, Richard L., Berman, Russell S., Pavlick, Anna C., Chapman, Paul B., Osman, Iman, Polsky, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867452/
https://ncbi.nlm.nih.gov/pubmed/17384209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.060135
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