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BET and BRAF inhibitors act synergistically against BRAF‐mutant melanoma
Despite major advances in the treatment of metastatic melanoma, treatment failure is still inevitable in most cases. Manipulation of key epigenetic regulators, including inhibition of Bromodomain and extra‐terminal domain (BET) family members impairs cell proliferation in vitro and tumor growth in v...
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| Publicado no: | Cancer Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867668/ https://ncbi.nlm.nih.gov/pubmed/27169980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.667 |
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