Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage

Clearance of apoptotic cells by macrophages plays an important role in maintaining tissue homeostasis. Previous study indicated that streptococcal pyrogenic exotoxin B (SPE B) reduces phagocytic activity in group A streptococcus (GAS) infection. Here, we demonstrate that SPE B causes an inhibitory e...

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Publicado en:Sci Rep
Main Authors: Chen, Chia-Ling, Wu, Yueh-Ying, Lin, Chiou-Feng, Kuo, Chih-Feng, Han, Chia-Li, Wang, Shuying, Chuang, Woei-Jer, Chen, Chiu-Yueh, Wu, Jiunn-Jong, Tsai, Pei-Jane, Liu, Ching-Chuan, Lin, Yee-Shin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867609/
https://ncbi.nlm.nih.gov/pubmed/27181595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26026
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