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Streptococcal Pyrogenic Exotoxin B-Induced Apoptosis in A549 Cells Is Mediated through α(v)β(3) Integrin and Fas
Our previous work suggested that streptococcal pyrogenic exotoxin (SPE) B-induced apoptosis is mediated through a receptor-like mechanism. In this study, we have identified α(v)β(3) and Fas as the SPE B receptors for this function. The SPE B fragment without the RGD motif and G308S, a SPE B mutant w...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology (ASM)
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292884/ https://ncbi.nlm.nih.gov/pubmed/18227168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01162-07 |
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