Streptococcal Pyrogenic Exotoxin B-Induced Apoptosis in A549 Cells Is Mediated through α(v)β(3) Integrin and Fas

Our previous work suggested that streptococcal pyrogenic exotoxin (SPE) B-induced apoptosis is mediated through a receptor-like mechanism. In this study, we have identified α(v)β(3) and Fas as the SPE B receptors for this function. The SPE B fragment without the RGD motif and G308S, a SPE B mutant w...

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Autori principali: Tsai, Wan-Hua, Chang, Chia-Wen, Lin, Yee-Shin, Chuang, Woei-Jer, Wu, Jiunn-Jong, Liu, Ching-Chuan, Tsai, Pei-Jane, Lin, Ming T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292884/
https://ncbi.nlm.nih.gov/pubmed/18227168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01162-07
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