Streptococcal Pyrogenic Exotoxin B-Induced Apoptosis in A549 Cells Is Mediated by a Receptor- and Mitochondrion-Dependent Pathway

It has been shown that streptococcal pyrogenic exotoxin B (SPE B) can induce cells to undergo apoptosis. The present study is to dissect the role of SPE B protease and SPE B protein in the apoptotic process of A549 cells and to elucidate the SPE B-induced apoptotic pathway. Recombinant SPE B (rSPE B...

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Udgivet i:Infect Immun
Main Authors: Tsai, Wan-Hua, Chang, Chia-Wen, Chuang, Woei-Jer, Lin, Yee-Shin, Wu, Jiunn-Jong, Liu, Ching-Chuan, Chang, Wen-Tsan, Lin, Ming T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15557629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.12.7055-7062.2004
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