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Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors

[Image: see text] N,N-Diphenylamines were discovered as potent and selective EPAC2 inhibitors. A study was conducted to determine the structure–activity relationships in a series of inhibitors of which several compounds displayed submicromolar potencies. Selectivity over the related EPAC1 protein wa...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Wild, Christopher T., Zhu, Yingmin, Na, Ye, Mei, Fang, Ynalvez, Marcus A., Chen, Haiying, Cheng, Xiaodong, Zhou, Jia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867506/
https://ncbi.nlm.nih.gov/pubmed/27190593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00477
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