Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

[Image: see text] The identification of a new series of P. falciparum growth inhibitors is described. Starting from a series of known human class I HDAC inhibitors a SAR exploration based on growth inhibitory activity in parasite and human cells-based assays led to the identification of compounds wi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:ACS Med Chem Lett
Päätekijät: Ontoria, Jesus M., Paonessa, Giacomo, Ponzi, Simona, Ferrigno, Federica, Nizi, Emanuela, Biancofiore, Ilaria, Malancona, Savina, Graziani, Rita, Roberts, David, Willis, Paul, Bresciani, Alberto, Gennari, Nadia, Cecchetti, Ottavia, Monteagudo, Edith, Orsale, Maria V., Veneziano, Maria, Di Marco, Annalise, Cellucci, Antonella, Laufer, Ralph, Altamura, Sergio, Summa, Vincenzo, Harper, Steven
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2016
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867480/
https://ncbi.nlm.nih.gov/pubmed/27190592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00468
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia