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Novel Inhibitors of Toxin HipA Reduce Multidrug Tolerant Persisters
[Image: see text] Persisters are a small fraction of drug-tolerant bacteria without any genotype variations. Their existence in many life-threatening infectious diseases presents a major challenge to antibiotic therapy. Persistence is highly related to toxin–antitoxin modules. HipA (high persistence...
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| Udgivet i: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2016
|
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867474/ https://ncbi.nlm.nih.gov/pubmed/27190591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00420 |
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