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Molecular Mechanisms of HipA Mediated Multidrug Tolerance and its Neutralization by HipB

Bacterial multidrug tolerance is largely responsible for the inability of antibiotics to eradicate infections and is caused by a small population of dormant bacteria called persisters. HipA is a critical Escherichia coli persistence factor that is normally neutralized by HipB, a transcription repres...

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Bibliographic Details
Main Authors: Schumacher, Maria A., Piro, Kevin M., Xu, Weijun, Hansen, Sonja, Lewis, Kim, Brennan, Richard G.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764309/
https://ncbi.nlm.nih.gov/pubmed/19150849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163806
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