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Novel Inhibitors of Toxin HipA Reduce Multidrug Tolerant Persisters

[Image: see text] Persisters are a small fraction of drug-tolerant bacteria without any genotype variations. Their existence in many life-threatening infectious diseases presents a major challenge to antibiotic therapy. Persistence is highly related to toxin–antitoxin modules. HipA (high persistence...

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Bibliografiska uppgifter
I publikationen:ACS Med Chem Lett
Huvudupphovsmän: Li, Tongqing, Yin, Ning, Liu, Hongbo, Pei, Jianfeng, Lai, Luhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2016
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867474/
https://ncbi.nlm.nih.gov/pubmed/27190591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00420
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