The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

Glucocorticoids (GCs) have been widely used for decades as a first-line treatment for inflammatory and autoimmune diseases. However, their use is often hampered by the onset of adverse effects or resistance. GCs mediate their effects via binding to glucocorticoid receptor (GR), a transcription facto...

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Pubblicato in:Microbiol Mol Biol Rev
Autori principali: Petta, Ioanna, Dejager, Lien, Ballegeer, Marlies, Lievens, Sam, Tavernier, Jan, De Bosscher, Karolien, Libert, Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Reviews
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867367/
https://ncbi.nlm.nih.gov/pubmed/27169854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00064-15
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