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Post-transcriptional m(6)A editing of HIV-1 mRNAs enhances viral gene expression

Covalent addition of a methyl group to the adenosine N(6) (m(6)A) is an evolutionarily conserved and common RNA modification that is thought to modulate several aspects of RNA metabolism. While the presence of multiple m(6)A editing sites on diverse viral RNAs was reported starting almost 40 years a...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Kennedy, Edward M., Bogerd, Hal P., Kornepati, Anand V. R., Kang, Dong, Ghoshal, Delta, Marshall, Joy B., Poling, Brigid C., Tsai, Kevin, Gokhale, Nandan S., Horner, Stacy M., Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867121/
https://ncbi.nlm.nih.gov/pubmed/27117054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.04.002
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