Regulatory T-cell activity but not conventional HIV-specific T-cell responses are associated with protection from HIV-1 infection

OBJECTIVE: Two distinct hypotheses have been proposed for T-cell involvement in protection from HIV-1 acquisition. First, HIV-1-specific memory T-cell responses generated upon HIV-1 exposure could mount an efficient response to HIV-1 and inhibit the establishment of an infection. Second, a lower lev...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Pattacini, Laura, Baeten, Jared M., Thomas, Katherine K., Fluharty, Tayler R., Murnane, Pamela M., Donnell, Deborah, Bukusi, Elizabeth, Ronald, Allan, Mugo, Nelly, Lingappa, Jairam R., Celum, Connie, McElrath, M. Juliana, Lund, Jennifer M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866890/
https://ncbi.nlm.nih.gov/pubmed/26656786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000919
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