Using Plasma Viral Load to Guide Antiretroviral Therapy Initiation to Prevent HIV-1 Transmission

BACKGROUND: Current WHO guidelines recommend antiretroviral therapy (ART) initiation at CD4 counts ≤350 cells/µL. Increasing this threshold has been proposed, with a primary goal of reducing HIV-1 infectiousness. Because the quantity of HIV-1 in plasma is the primary predictor of HIV-1 transmission,...

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Bibliographic Details
Main Authors: Murnane, Pamela M., Hughes, James P., Celum, Connie, Lingappa, Jairam R., Mugo, Nelly, Farquhar, Carey, Kiarie, James, Wald, Anna, Baeten, Jared M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511400/
https://ncbi.nlm.nih.gov/pubmed/23250272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051192
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