Regulatory T-cell activity but not conventional HIV-specific T-cell responses are associated with protection from HIV-1 infection

OBJECTIVE: Two distinct hypotheses have been proposed for T-cell involvement in protection from HIV-1 acquisition. First, HIV-1-specific memory T-cell responses generated upon HIV-1 exposure could mount an efficient response to HIV-1 and inhibit the establishment of an infection. Second, a lower lev...

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Bibliographic Details
Published in:J Acquir Immune Defic Syndr
Main Authors: Pattacini, Laura, Baeten, Jared M., Thomas, Katherine K., Fluharty, Tayler R., Murnane, Pamela M., Donnell, Deborah, Bukusi, Elizabeth, Ronald, Allan, Mugo, Nelly, Lingappa, Jairam R., Celum, Connie, McElrath, M. Juliana, Lund, Jennifer M.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866890/
https://ncbi.nlm.nih.gov/pubmed/26656786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000919
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