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Regulatory T-cell activity but not conventional HIV-specific T-cell responses are associated with protection from HIV-1 infection

OBJECTIVE: Two distinct hypotheses have been proposed for T-cell involvement in protection from HIV-1 acquisition. First, HIV-1-specific memory T-cell responses generated upon HIV-1 exposure could mount an efficient response to HIV-1 and inhibit the establishment of an infection. Second, a lower lev...

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Xehetasun bibliografikoak
Argitaratua izan da:J Acquir Immune Defic Syndr
Egile Nagusiak: Pattacini, Laura, Baeten, Jared M., Thomas, Katherine K., Fluharty, Tayler R., Murnane, Pamela M., Donnell, Deborah, Bukusi, Elizabeth, Ronald, Allan, Mugo, Nelly, Lingappa, Jairam R., Celum, Connie, McElrath, M. Juliana, Lund, Jennifer M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866890/
https://ncbi.nlm.nih.gov/pubmed/26656786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000919
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