Recombinant Production of Enzymatically Active Male Contraceptive Drug Target hTSSK2 - Localization of the TSKS Domain Phosphorylated by TSSK2

The testis-specific serine/threonine kinase 2 (TSSK2) has been proposed as a candidate male contraceptive target. Development of a selective inhibitor for this kinase first necessitates the production of highly purified, soluble human TSSK2 and its substrate, TSKS, with high yields and retention of...

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Bibliografiset tiedot
Julkaisussa:Protein Expr Purif
Päätekijät: Shetty, Jagathpala, Sinville, Rondedrick, Shumilin, Igor A., Minor, Wladek, Zhang, Jianhai, Hawkinson, Jon E., Georg, Gunda I., Flickinger, Charles J., Herr, John C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866589/
https://ncbi.nlm.nih.gov/pubmed/26777341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2016.01.009
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