Enhancing NAD(+) Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1)

Nicotinamide adenine dinucleotide (NAD(+)) participates in redox reactions and NAD(+)-dependent signaling pathways. Although the redox reactions are critical for efficient mitochondrial metabolism, they are not accompanied by any net consumption of the nucleotide. On the contrary, NAD(+)-dependent s...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Harlan, Benjamin A., Pehar, Mariana, Sharma, Deep R., Beeson, Gyda, Beeson, Craig C., Vargas, Marcelo R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Molecular Bases of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865928/
https://ncbi.nlm.nih.gov/pubmed/27002158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698779
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