Ubiquitin-specific Peptidase 10 (USP10) Deubiquitinates and Stabilizes MutS Homolog 2 (MSH2) to Regulate Cellular Sensitivity to DNA Damage

MSH2 is a key DNA mismatch repair protein, which plays an important role in genomic stability. In addition to its DNA repair function, MSH2 serves as a sensor for DNA base analogs-provoked DNA replication errors and binds to various DNA damage-induced adducts to trigger cell cycle arrest or apoptosi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Zhang, Mu, Hu, Chen, Tong, Dan, Xiang, Shengyan, Williams, Kendra, Bai, Wenlong, Li, Guo-Min, Bepler, Gerold, Zhang, Xiaohong
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2016
Θέματα:
Enzymology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865924/
https://ncbi.nlm.nih.gov/pubmed/26975374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.700047
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