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Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin
β-catenin is not only a key component of adherens junctions but also a transcriptional co-activator downstream of canonical Wnt signaling. The Wnt/β-catenin pathway plays critical roles in animal development and tissue homeostasis, while mutation or overexpression of β-catenin often leads to tumorig...
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| Pubblicato in: | Am J Cancer Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
e-Century Publishing Corporation
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176183/ https://ncbi.nlm.nih.gov/pubmed/30323974 |
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