Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17

IL-23 (interleukin 23) regulates immune responses against pathogens and plays a major role in the differentiation and maintenance of T(H)17 cells and the development of autoimmune diseases and cancer. The IL-23 receptor (IL-23R) complex consists of the unique IL-23R and the common IL-12 receptor β1...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Franke, Manuel, Schröder, Jutta, Monhasery, Niloufar, Ackfeld, Theresa, Hummel, Thorben M., Rabe, Björn, Garbers, Christoph, Becker-Pauly, Christoph, Floss, Doreen M., Scheller, Jürgen
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865905/
https://ncbi.nlm.nih.gov/pubmed/26961870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710541
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