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GNF-2 inhibits dengue virus by targeting Abl kinases and the viral E protein

Dengue virus infects over 300 million people annually, yet there is no widely protective vaccine or drugs against the virus. Efforts to develop antivirals against classical targets such as the viral protease and polymerase have not yielded drugs that have advanced to the clinic. Here we show that th...

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Bibliografische gegevens
Gepubliceerd in:Cell Chem Biol
Hoofdauteurs: Clark, Margaret J., Miduturu, Chandra, Schmidt, Aaron G., Zhu, Xuling, Pitts, Jared D., Wang, Jinhua, Potisopon, Supanee, Zhang, Jianming, Wojciechowski, Amy, Chu, Justin Jang Hann, Gray, Nathanael S., Yang, Priscilla L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865888/
https://ncbi.nlm.nih.gov/pubmed/27105280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.03.010
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