Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein

Viral envelope proteins are required for productive viral entry and initiation of infection. Although the humoral immune system provides ample evidence for targeting envelope proteins as an antiviral strategy, there are few pharmacological interventions that have this mode of action. In contrast to...

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Publicado en:Cell Chem Biol
Autores principales: de Wispelaere, Melissanne, Lian, Wenlong, Potisopon, Supanee, Li, Pi-Chun, Jang, Jaebong, Ficarro, Scott, Clark, Margaret J., Zhu, Xuling, Kaplan, Jenifer B., Pitts, Jared D., Wales, Thomas E., Wang, Jinhua, Engen, John R., Marto, Jarrod, Gray, Nathanael S., Yang, Priscilla L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097893/
https://ncbi.nlm.nih.gov/pubmed/29937406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.05.011
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