Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein

Viral envelope proteins are required for productive viral entry and initiation of infection. Although the humoral immune system provides ample evidence for targeting envelope proteins as an antiviral strategy, there are few pharmacological interventions that have this mode of action. In contrast to...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Chem Biol
Auteurs principaux: de Wispelaere, Melissanne, Lian, Wenlong, Potisopon, Supanee, Li, Pi-Chun, Jang, Jaebong, Ficarro, Scott, Clark, Margaret J., Zhu, Xuling, Kaplan, Jenifer B., Pitts, Jared D., Wales, Thomas E., Wang, Jinhua, Engen, John R., Marto, Jarrod, Gray, Nathanael S., Yang, Priscilla L.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097893/
https://ncbi.nlm.nih.gov/pubmed/29937406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.05.011
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