GNF-2 inhibits dengue virus by targeting Abl kinases and the viral E protein

Dengue virus infects over 300 million people annually, yet there is no widely protective vaccine or drugs against the virus. Efforts to develop antivirals against classical targets such as the viral protease and polymerase have not yielded drugs that have advanced to the clinic. Here we show that th...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Clark, Margaret J., Miduturu, Chandra, Schmidt, Aaron G., Zhu, Xuling, Pitts, Jared D., Wang, Jinhua, Potisopon, Supanee, Zhang, Jianming, Wojciechowski, Amy, Chu, Justin Jang Hann, Gray, Nathanael S., Yang, Priscilla L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865888/
https://ncbi.nlm.nih.gov/pubmed/27105280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.03.010
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