GNF-2 inhibits dengue virus by targeting Abl kinases and the viral E protein

Dengue virus infects over 300 million people annually, yet there is no widely protective vaccine or drugs against the virus. Efforts to develop antivirals against classical targets such as the viral protease and polymerase have not yielded drugs that have advanced to the clinic. Here we show that th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Chem Biol
Auteurs principaux: Clark, Margaret J., Miduturu, Chandra, Schmidt, Aaron G., Zhu, Xuling, Pitts, Jared D., Wang, Jinhua, Potisopon, Supanee, Zhang, Jianming, Wojciechowski, Amy, Chu, Justin Jang Hann, Gray, Nathanael S., Yang, Priscilla L.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865888/
https://ncbi.nlm.nih.gov/pubmed/27105280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.03.010
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