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Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

Large-scale sequencing projects are uncovering a growing number of missense mutations in human tumors. Understanding the phenotypic consequences of these alterations represents a formidable challenge. In silico prediction of functionally relevant amino acid motifs disrupted by cancer mutations could...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Prieto, Gorka, Fullaondo, Asier, Rodríguez, Jose A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865848/
https://ncbi.nlm.nih.gov/pubmed/27174732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25869
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