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Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

Large-scale sequencing projects are uncovering a growing number of missense mutations in human tumors. Understanding the phenotypic consequences of these alterations represents a formidable challenge. In silico prediction of functionally relevant amino acid motifs disrupted by cancer mutations could...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Prieto, Gorka, Fullaondo, Asier, Rodríguez, Jose A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865848/
https://ncbi.nlm.nih.gov/pubmed/27174732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25869
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