Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity

AIM: Assuming that genetic variants of the SLC22A2 and SLC31A1 transporter affect patients’ susceptibility to cisplatin-induced ototoxicity, we compared the distribution of 11 SLC22A2 variants and the SLC31A1 variant rs10981694 between patients with and without cisplatin-induced ototoxicity. PATIENT...

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Publicat a:Pharmacogenomics
Autors principals: Lanvers-Kaminsky, Claudia, Sprowl, Jason A, Malath, Ingrid, Deuster, Dirk, Eveslage, Maria, Schlatter, Eberhard, Mathijssen, Ron HJ, Boos, Joachim, Jürgens, Heribert, am Zehnhoff-Dinnesen, Antionette G, Sparreboom, Alex, Ciarimboli, Giuliano
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865798/
https://ncbi.nlm.nih.gov/pubmed/25823781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.182
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