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Acid‐sensing ion channels are tuned to follow high‐frequency stimuli

KEY POINTS: Acid‐sensing ion channels (ASICs) act as neurotransmitter receptors by responding to synaptic cleft acidification. We investigated how ASIC1a homomers and ASIC1a/2a heteromers respond to brief stimuli, jumping from pH 8.0 to 5.0, approximating the time course of neurotransmitter in the c...

詳細記述

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書誌詳細
出版年:J Physiol
主要な著者: MacLean, David M., Jayaraman, Vasanthi
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865573/
https://ncbi.nlm.nih.gov/pubmed/26931316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271915
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