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Intracellular soluble α‐synuclein oligomers reduce pyramidal cell excitability
KEY POINTS: The presynaptic protein α‐synuclein forms aggregates during Parkinson's disease. Accumulating evidence suggests that the small soluble oligomers of α‐synuclein are more toxic than the larger aggregates appearing later in the disease. The link between oligomer toxicity and structure...
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| Publicado en: | J Physiol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865569/ https://ncbi.nlm.nih.gov/pubmed/26915902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271968 |
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