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Real-time HD Exchange Kinetics of Proteins from Buffered Aqueous Solution with Electrothermal Supercharging and Top-Down Tandem Mass Spectrometry

Electrothermal supercharging (ETS) with electrospray ionization produces highly charged protein ions from buffered aqueous solutions in which proteins have native folded structures. ETS increases the charge of ribonuclease A by 34% whereas only a 6% increase in charge occurs for a reduced alkylated...

詳細記述

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書誌詳細
出版年:J Am Soc Mass Spectrom
主要な著者: Going, Catherine C., Xia, Zijie, Williams, Evan R.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865425/
https://ncbi.nlm.nih.gov/pubmed/26919868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1350-z
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