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Implications of human TRPM8 channel gating from menthol binding studies of the sensing domain
The transient receptor potential melastatin 8 (TRPM8) ion channel is the primary cold sensor in humans. TRPM8 is gated by physiologically relevant cold temperatures and chemical ligands that induce cold sensations, such as the analgesic compound menthol. Characterization of TRPM8 ligand-gated channe...
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| Vydáno v: | Biochemistry |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865251/ https://ncbi.nlm.nih.gov/pubmed/26653082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00931 |
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