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Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP(2) Suggest a Mechanism for Regulation

TRPM8 is a member of the transient receptor potential ion channel family where it functions as a cold and pain sensor in humans and other higher organisms. Previous studies show that TRPM8 requires the signaling phosphoinositide lipid PIP(2) to function. TRPM8 function is further regulated by other...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Sisco, Nicholas J., Helsell, Cole V. M., Van Horn, Wade D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773951/
https://ncbi.nlm.nih.gov/pubmed/31575973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49912-5
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