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Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels

Transient receptor potential melastatin 8 (TRPM8) is a cold-sensitive ion channel with diverse physiological roles. TRPM8 activity is modulated by many mechanisms, including an interaction with the small membrane protein phosphoinositide-interacting regulator of TRP (PIRT). Here, using comparative e...

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Опубликовано в: :J Biol Chem
Главные авторы: Hilton, Jacob K., Salehpour, Taraneh, Sisco, Nicholas J., Rath, Parthasarathi, Van Horn, Wade D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005438/
https://ncbi.nlm.nih.gov/pubmed/29724821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003563
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