8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice

PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand and has higher activity than EPA. However, to dat...

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Bibliographische Detailangaben
Veröffentlicht in:J Lipids
Hauptverfasser: Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Motodate, Kaori, Nagahora, Nozomi, Hirose, Masamichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864551/
https://ncbi.nlm.nih.gov/pubmed/27239345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7498508
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