8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice

PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand and has higher activity than EPA. However, to dat...

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Detaylı Bibliyografya
Yayımlandı:J Lipids
Asıl Yazarlar: Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Motodate, Kaori, Nagahora, Nozomi, Hirose, Masamichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864551/
https://ncbi.nlm.nih.gov/pubmed/27239345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7498508
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