Hydroxyeicosapentaenoic acids from the Pacific krill show high ligand activities for PPARs

PPARs regulate the expression of genes for energy metabolism in a ligand-dependent manner. PPARs can influence fatty acid oxidation, the level of circulating triglycerides, glucose uptake and insulin sensitivity. Here, we demonstrate that 5-hydroxyeicosapentaenoic acid (HEPE), 8-HEPE, 9-HEPE, 12-HEP...

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Detalhes bibliográficos
Main Authors: Yamada, Hidetoshi, Oshiro, Eriko, Kikuchi, Sayaka, Hakozaki, Mayuka, Takahashi, Hideyuki, Kimura, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995467/
https://ncbi.nlm.nih.gov/pubmed/24668940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047514
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