8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice

PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand and has higher activity than EPA. However, to dat...

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Detalhes bibliográficos
Publicado no:J Lipids
Main Authors: Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Motodate, Kaori, Nagahora, Nozomi, Hirose, Masamichi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864551/
https://ncbi.nlm.nih.gov/pubmed/27239345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7498508
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