8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice

PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand and has higher activity than EPA. However, to dat...

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Dades bibliogràfiques
Publicat a:J Lipids
Autors principals: Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Motodate, Kaori, Nagahora, Nozomi, Hirose, Masamichi
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864551/
https://ncbi.nlm.nih.gov/pubmed/27239345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7498508
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