8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice

PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand and has higher activity than EPA. However, to dat...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Lipids
Glavni autori: Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Motodate, Kaori, Nagahora, Nozomi, Hirose, Masamichi
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864551/
https://ncbi.nlm.nih.gov/pubmed/27239345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7498508
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