Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-α

BACKGROUND AND PURPOSE: Combining statin and fibrate in clinical practice provides a greater reduction of triglycerides than either drug given alone, but the mechanism for this effect is poorly understood. Apolipoprotein AV (apoAV) has been implicated in triglyceride metabolism. This study was desig...

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Detalhes bibliográficos
Main Authors: Huang, Xian-sheng, Zhao, Shui-ping, Bai, Lin, Hu, Min, Zhao, Wang, Zhang, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765591/
https://ncbi.nlm.nih.gov/pubmed/19694729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00350.x
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