Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-α

BACKGROUND AND PURPOSE: Combining statin and fibrate in clinical practice provides a greater reduction of triglycerides than either drug given alone, but the mechanism for this effect is poorly understood. Apolipoprotein AV (apoAV) has been implicated in triglyceride metabolism. This study was desig...

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Bibliographic Details
Main Authors: Huang, Xian-sheng, Zhao, Shui-ping, Bai, Lin, Hu, Min, Zhao, Wang, Zhang, Qian
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765591/
https://ncbi.nlm.nih.gov/pubmed/19694729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00350.x
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