Effect of the specific proteasome inhibitor bortezomib on cancer‐related muscle wasting

BACKGROUND: Muscle wasting, a prominent feature of cancer cachexia, is mainly caused by sustained protein hypercatabolism. The enhanced muscle protein degradation rates rely on the activity of different proteolytic systems, although the Adenosine triphosphate (ATP)‐ubiquitin‐proteasome‐dependent pat...

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Библиографические подробности
Опубликовано в: :J Cachexia Sarcopenia Muscle
Главные авторы: Penna, Fabio, Bonetto, Andrea, Aversa, Zaira, Minero, Valerio Giacomo, Rossi Fanelli, Filippo, Costelli, Paola, Muscaritoli, Maurizio
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864285/
https://ncbi.nlm.nih.gov/pubmed/27239411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12050
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