Effect of the specific proteasome inhibitor bortezomib on cancer‐related muscle wasting

BACKGROUND: Muscle wasting, a prominent feature of cancer cachexia, is mainly caused by sustained protein hypercatabolism. The enhanced muscle protein degradation rates rely on the activity of different proteolytic systems, although the Adenosine triphosphate (ATP)‐ubiquitin‐proteasome‐dependent pat...

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Bibliografiske detaljer
Udgivet i:J Cachexia Sarcopenia Muscle
Main Authors: Penna, Fabio, Bonetto, Andrea, Aversa, Zaira, Minero, Valerio Giacomo, Rossi Fanelli, Filippo, Costelli, Paola, Muscaritoli, Maurizio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864285/
https://ncbi.nlm.nih.gov/pubmed/27239411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12050
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