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Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

TRIM E3 ubiquitin ligases regulate a wide variety of cellular processes and are particularly important during innate immune signalling events. They are characterized by a conserved tripartite motif in their N‐terminal portion which comprises a canonical RING domain, one or two B‐box domains and a co...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Koliopoulos, Marios G, Esposito, Diego, Christodoulou, Evangelos, Taylor, Ian A, Rittinger, Katrin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864278/
https://ncbi.nlm.nih.gov/pubmed/27154206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593741
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