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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863743/
https://ncbi.nlm.nih.gov/pubmed/27151974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278424.116
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