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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863743/
https://ncbi.nlm.nih.gov/pubmed/27151974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278424.116
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